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ST 271
CAS No. 106392-48-7
ST 271 ( ST-271 | ST271 | ST 271 )
产品货号. M17133 CAS No. 106392-48-7
ST271 是一种有效的蛋白酪氨酸激酶 (PTK) 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥292 | 有现货 |
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| 5MG | ￥446 | 有现货 |
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| 10MG | ￥721 | 有现货 |
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| 25MG | ￥1288 | 有现货 |
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| 50MG | ￥2203 | 有现货 |
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| 100MG | ￥3540 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ST 271
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ST271 是一种有效的蛋白酪氨酸激酶 (PTK) 抑制剂。
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产品描述ST-271 is tyrphostin tyrosine kinase inhibitor. ST271 reduced intracellular Ca2+ levels and inhibited activation of phospholipase C. Elevation of intracellular Ca2+ regulates agonist-induced activation of phospholipase C and that this contributes to the inhibition of thrombin-induced formation of inositol phosphates by the tyrphostin ST271.
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体外实验ST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30%) but significant inhibition of the response to thrombin and U46619.
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体内实验——
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同义词ST-271 | ST271 | ST 271
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通路Others
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靶点Other Targets
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受体PTK
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研究领域——
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适应症——
化学信息
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CAS Number106392-48-7
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分子量272.34
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分子式C16H20N2O2
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 110 mg/mL 403.91 mM
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SMILESCC(C)c1cc(cc(c1O)C(C)C)/C=C(\C#N)/C(=O)N
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化学全称(E)-2-Cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34.
